Science-Single-stranded DNA and RNA origami

Single-stranded DNA and RNA origami

Dongran Han1,2,*, Xiaodong Qi3,4,*, Cameron Myhrvold1,2, Bei Wang2,5, Mingjie Dai1,2, Shuoxing Jiang3,4, Maxwell Bates6, Yan Liu3,4, Byoungkwon An6,†, Fei Zhang3,4,†, Hao Yan3,4,†, Peng Yin1,2,†
1.Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
2.Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
3.Biodesign Center for Molecular Design and Biomimetics Biodesign Institute, Tempe, AZ 85287, USA.
4.School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA.
5.Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.
6.BioNano Research Group, Autodesk Life Sciences, Pier 9, San Francisco, CA 94111, USA.

Science  15 Dec 2017:
Vol. 358, Issue 6369, eaao2648
DOI: 10.1126/science.aao2648
© 2017 American Association for the Advancement of Science. All rights reserved. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. Science ISSN 1095-9203

Unimolecular folding of single-stranded DNA and RNA origami into user-specified shapes.

3D animation: